講演会のおしらせ【2014.4.18】(2014.03.17更新)
| 演題 | Linking angiogenesis and metabolism by FOXO transcription factors |
|---|---|
| 演者 | Michael Potente, MD, PhD |
| 所属 | Max Planck Institute for Heart and Lung Research Angiogenesis & Metabolism Laboratory, Ludwigstr. 43, D-61231 Bad Nauheim, Germany |
| 日時 | 2014年4月18日（金）pm6:00 - 7:30 |
| 場所 | 札幌医科大学基礎医学研究棟5F会議室 |
| 共催 | 日本生化学会北海道支部 |
| 概要 | [講演内容要旨]
Blood vessels form the first organ in the developing embryo and build extensive networks that supply all cells with nutrients and oxygen throughout life. As blood vessels get older, they often become abnormal in structure and function, thereby contributing to numerous age-associated diseases including ischemic heart and brain disease, neurodegeneration, or cancer. First described as regulators of the aging process in invertebrate model organisms, Forkhead box "O" (FOXO) transcription factors and sirtuin deacetylases are now emerging as key regulators of mammalian vascular development and disease. The integration of individual FOXO and sirtuin family members into various aspects of vessel growth, maintenance, and function provides new perspectives on disease mechanisms of aging, the most important risk factor for medical maladies of the vascular system. [コメント]
Potente先生はNotchのアセチル化修飾を発見した気鋭のvascular biologistです。今回、京都でおこなわれる第18回国際血管生物会議で来日されるため、札幌にお呼びして講演会を開催することになりました。ご業績はNature 495, 107, 2013; Nature 473, 234, 2011; Dev Cell 16, 70, 2009; Genes Dev 21, 2644, 2007などです。 |
| 連絡先 |
講演会案内【WORD】（280KB）